| 2021-05-22 18:30:55Saturday, May 22, 2021 | Berwick Bandits v Birmingham Brummies | 18:30:556:30 pm | 39 - 51 | Championship | Shielfield Park |
| 2021-06-02 19:30:30Wednesday, June 2, 2021 | Birmingham Brummies v Redcar Bears | 19:30:30Abandoned | 23 - 31 | Championship KO Cup, 1st Round, 1st Leg | Perry Barr Stadium |
| 2021-06-04 19:30:02Friday, June 4, 2021 | Redcar Bears v Birmingham Brummies | 19:30:027:30 pm | 46 - 44 | Championship KO Cup, 1st Round, 1st Leg | Media Prima Arena |
| 2021-06-09 19:30:30Wednesday, June 9, 2021 | Birmingham Brummies v Glasgow Tigers | 19:30:307:30 pm | 42 - 48 | Championship | Perry Barr Stadium |
| 2021-06-16 00:05:30Wednesday, June 16, 2021 | Birmingham Brummies v Poole Pirates | 00:05:30Postponed | P - P | Championship | Perry Barr Stadium |
| 2021-07-07 00:05:30Wednesday, July 7, 2021 | Birmingham Brummies v Redcar Bears | 00:05:30Postponed | P - P | Championship KO Cup, 1st Round, 2nd Leg | Perry Barr Stadium |
| 2021-07-09 19:30:02Friday, July 9, 2021 | Redcar Bears v Birmingham Brummies | 19:30:027:30 pm | 48 - 42 | Championship | Media Prima Arena |
| 2021-07-14 19:30:30Wednesday, July 14, 2021 | Birmingham Brummies v Scunthorpe Scorpions | 19:30:307:30 pm | 39 - 51 | Championship | Perry Barr Stadium |
| 2021-07-21 19:30:43Wednesday, July 21, 2021 | Birmingham Brummies v Redcar Bears | 19:30:437:30 pm | 55 - 35 | Championship KO Cup, 1st Round, 2nd Leg | Perry Barr Stadium |
| 2021-07-28 11:00:30Wednesday, July 28, 2021 | Birmingham Brummies v Plymouth Gladiators | 11:00:30Postponed | P - P | Championship | Perry Barr Stadium |
| 2021-07-30 19:30:30Friday, July 30, 2021 | Edinburgh Monarchs v Birmingham Brummies | 19:30:30Abandoned | 26 - 16 | Championship KO Cup, Quarter-Final, 1st Leg | Armadale Stadium |
| 2021-07-31 19:00:16Saturday, July 31, 2021 | Leicester Lions v Birmingham Brummies | 19:00:167:00 pm | 63 - 27 | Championship | Paul Chapman & Sons Arena |
| 2021-08-04 19:30:30Wednesday, August 4, 2021 | Birmingham Brummies v Kent Kings | 19:30:307:30 pm | 46 - 44 | Championship | Perry Barr Stadium |
| 2021-08-07 00:05:57Saturday, August 7, 2021 | Eastbourne Eagles v Birmingham Brummies | 00:05:57Postponed | P - P | Championship | Arlington Stadium |
| 2021-08-11 19:30:30Wednesday, August 11, 2021 | Birmingham Brummies v Leicester Lions | 19:30:307:30 pm | 46 - 44 | Championship | Perry Barr Stadium |
| 2021-08-13 08:20:24Friday, August 13, 2021 | Glasgow Tigers v Birmingham Brummies | 08:20:24Postponed | P - P | Championship | Peugeot Ashfield Stadium |
| 2021-08-18 19:30:30Wednesday, August 18, 2021 | Birmingham Brummies v Berwick Bandits | 19:30:307:30 pm | 53 - 37 | Championship | Perry Barr Stadium |
| 2021-08-20 19:30:26Friday, August 20, 2021 | Scunthorpe Scorpions v Birmingham Brummies | 19:30:267:30 pm | 52 - 38 | Championship | Eddie Wright Raceway |
| 2021-08-24 19:00:08Tuesday, August 24, 2021 | Plymouth Gladiators v Birmingham Brummies | 19:00:087:00 pm | 47 - 42 | Championship | Plymouth Coliseum |
| 2021-08-25 19:30:54Wednesday, August 25, 2021 | Birmingham Brummies v Plymouth Gladiators | 19:30:547:30 pm | 54 - 36 | Championship | Perry Barr Stadium |
| 2021-08-29 17:00:21Sunday, August 29, 2021 | Poole Pirates v Birmingham Brummies | 17:00:215:00 pm | 57 - 33 | Championship | Poole Stadium |
| 2021-08-30 16:00:59Monday, August 30, 2021 | Kent Kings v Birmingham Brummies | 16:00:594:00 pm | 50 - 40 | Championship | Central Park Stadium |
| 2021-09-01 19:30:03Wednesday, September 1, 2021 | Birmingham Brummies v Poole Pirates | 19:30:037:30 pm | 49 - 41 | Championship | Perry Barr Stadium |
| 2021-09-03 19:30:59Friday, September 3, 2021 | Edinburgh Monarchs v Birmingham Brummies | 19:30:597:30 pm | 45 - 45 | Championship | Armadale Stadium |
| 2021-09-08 19:30:59Wednesday, September 8, 2021 | Birmingham Brummies v Redcar Bears | 19:30:597:30 pm | 42 - 48 | Championship | Perry Barr Stadium |
| 2021-09-10 19:30:39Friday, September 10, 2021 | Edinburgh Monarchs v Birmingham Brummies | 19:30:397:30 pm | 54 - 36 | Championship KO Cup, Quarter-Final, 1st Leg | Armadale Stadium |
| 2021-09-15 19:30:30Wednesday, September 15, 2021 | Birmingham Brummies v Edinburgh Monarchs | 19:30:307:30 pm | 52 - 38 | Championship | Perry Barr Stadium |
| 2021-09-19 18:30:55Sunday, September 19, 2021 | Newcastle Diamonds v Birmingham Brummies | 18:30:556:30 pm | 44 - 45 | Championship | Newcastle Stadium |
| 2021-09-22 19:30:09Wednesday, September 22, 2021 | Birmingham Brummies v Newcastle Diamonds | 19:30:097:30 pm | 55 - 35 | Championship | Perry Barr Stadium |
| 2021-09-24 19:30:42Friday, September 24, 2021 | Glasgow Tigers v Birmingham Brummies | 19:30:427:30 pm | 49 - 41 | Championship | Peugeot Ashfield Stadium |
| 2021-09-29 19:30:24Wednesday, September 29, 2021 | Birmingham Brummies v Edinburgh Monarchs | 19:30:247:30 pm | 40 - 50 | Championship KO Cup, Quarter-Final, 2nd Leg | Perry Barr Stadium |
