| 2022-03-26 19:00:00Saturday, March 26, 2022 | Leicester Lions v Birmingham Brummies | 19:00:007:00 pm | 64 - 26 | Championship KO Cup, 1st Round, 1st Leg | Paul Chapman & Sons Arena |
| 2022-03-28 19:30:04Monday, March 28, 2022 | Wolverhampton Wolves v Brummies Past & Present | 19:30:047:30 pm | 56 - 34 | Challenge | Monmore Green |
| 2022-03-30 11:15:19Wednesday, March 30, 2022 | Birmingham Brummies v Coventry Bees Select | 11:15:19Postponed | P - P | Challenge | Perry Barr Stadium |
| 2022-04-02 19:00:00Saturday, April 2, 2022 | Berwick Bandits v Birmingham Brummies | 19:00:007:00 pm | 58 - 32 | Championship | Shielfield Park |
| 2022-04-06 19:30:00Wednesday, April 6, 2022 | Birmingham Brummies v Leicester Lions | 19:30:007:30 pm | 30 - 30 | Championship KO Cup, 1st Round, 2nd Leg | Perry Barr Stadium |
| 2022-04-13 14:50:00Wednesday, April 13, 2022 | Birmingham Brummies v Poole Pirates | 14:50:00Postponed | P - P | Championship | Perry Barr Stadium |
| 2022-04-15 19:30:00Friday, April 15, 2022 | Redcar Bears v Birmingham Brummies | 19:30:007:30 pm | 50 - 40 | Championship | ECCO Arena |
| 2022-04-20 19:30:00Wednesday, April 20, 2022 | Birmingham Brummies v Berwick Bandits | 19:30:00Abandoned | 8 - 4 | Championship | Perry Barr Stadium |
| 2022-04-22 19:30:00Friday, April 22, 2022 | Scunthorpe Scorpions v Birmingham Brummies | 19:30:007:30 pm | 54 - 36 | Championship | Eddie Wright Raceway |
| 2022-04-27 19:30:00Wednesday, April 27, 2022 | Poole Pirates v Birmingham Brummies | 19:30:007:30 pm | 54 - 36 | Championship | Poole Stadium |
| 2022-05-04 19:30:00Wednesday, May 4, 2022 | Birmingham Brummies v Scunthorpe Scorpions | 19:30:007:30 pm | 49 - 41 | Championship | Perry Barr Stadium |
| 2022-05-17 19:30:00Tuesday, May 17, 2022 | Oxford Cheetahs v Birmingham Brummies | 19:30:007:30 pm | 42 - 48 | Championship | Oxford Stadium |
| 2022-05-18 19:30:00Wednesday, May 18, 2022 | Birmingham Brummies v Oxford Cheetahs | 19:30:007:30 pm | 43 - 47 | Championship | Perry Barr Stadium |
| 2022-05-25 19:30:05Wednesday, May 25, 2022 | Birmingham Brummies v Poole Pirates | 19:30:057:30 pm | 35 - 55 | Championship | Perry Barr Stadium |
| 2022-05-27 19:30:00Friday, May 27, 2022 | Edinburgh Monarchs v Birmingham Brummies | 19:30:007:30 pm | 52 - 36 | Championship | Armadale Stadium |
| 2022-06-01 19:30:00Wednesday, June 1, 2022 | Birmingham Brummies v Leicester Lions | 19:30:007:30 pm | 38 - 52 | Championship | Perry Barr Stadium |
| 2022-06-07 08:09:00Tuesday, June 7, 2022 | Plymouth Gladiators v Birmingham Brummies | 08:09:00Postponed | P - P | Championship | Plymouth Coliseum |
| 2022-06-08 19:30:00Wednesday, June 8, 2022 | Birmingham Brummies v Edinburgh Monarchs | 19:30:007:30 pm | 40 - 50 | Championship | Perry Barr Stadium |
| 2022-06-15 19:30:00Wednesday, June 15, 2022 | Birmingham Brummies v Plymouth Gladiators | 19:30:007:30 pm | 46 - 44 | Championship | Perry Barr Stadium |
| 2022-06-22 19:30:00Wednesday, June 22, 2022 | Birmingham Brummies v Redcar Bears | 19:30:007:30 pm | 50 - 40 | Championship | Perry Barr Stadium |
| 2022-06-25 19:00:00Saturday, June 25, 2022 | Leicester Lions v Birmingham Brummies | 19:00:007:00 pm | 62 - 28 | Championship | Paul Chapman & Sons Arena |
| 2022-07-06 19:30:00Wednesday, July 6, 2022 | Birmingham Brummies v Glasgow Tigers | 19:30:007:30 pm | 33 - 57 | Championship | Perry Barr Stadium |
| 2022-07-12 19:00:00Tuesday, July 12, 2022 | Plymouth Gladiators v Birmingham Brummies | 19:00:007:00 pm | 57 - 32 | Championship Jubilee League (Southern) | Plymouth Coliseum |
| 2022-07-13 19:30:00Wednesday, July 13, 2022 | Birmingham Brummies v Plymouth Gladiators | 19:30:007:30 pm | 52 - 38 | Championship Jubilee League (Southern) | Perry Barr Stadium |
| 2022-07-19 19:30:00Tuesday, July 19, 2022 | Oxford Cheetahs v Birmingham Brummies | 19:30:007:30 pm | 56 - 34 | Championship Jubilee League (Southern) | Oxford Stadium |
| 2022-07-20 19:30:00Wednesday, July 20, 2022 | Birmingham Brummies v Oxford Cheetahs | 19:30:007:30 pm | 46 - 44 | Championship Jubilee League (Southern) | Perry Barr Stadium |
| 2022-07-27 19:30:00Wednesday, July 27, 2022 | Birmingham Brummies v Poole Pirates | 19:30:007:30 pm | 34 - 56 | Championship Jubilee League (Southern) | Perry Barr Stadium |
| 2022-07-29 19:30:00Friday, July 29, 2022 | Poole Pirates v Birmingham Brummies | 19:30:007:30 pm | 59 - 31 | Championship Jubilee League (Southern) | Poole Stadium |
| 2022-08-02 19:00:42Tuesday, August 2, 2022 | Plymouth Gladiators v Birmingham Brummies | 19:00:427:00 pm | 46 - 44 | Championship | Plymouth Coliseum |
| 2022-08-05 19:30:00Friday, August 5, 2022 | Glasgow Tigers v Birmingham Brummies | 19:30:007:30 pm | 56 - 34 | Championship | Peugeot Ashfield Stadium |
| 2022-08-10 19:30:30Wednesday, August 10, 2022 | Birmingham Brummies v Berwick Bandits | 19:30:307:30 pm | 48 - 42 | Championship | Perry Barr Stadium |
| 2022-08-17 19:30:37Wednesday, August 17, 2022 | Birmingham Brummies v Coventry Bees Select | 19:30:377:30 pm | 48 - 42 | Challenge | Perry Barr Stadium |
| 2022-09-07 15:40:49Wednesday, September 7, 2022 | Birmingham Brummies v Cradley Heathens Select | 15:40:49Postponed | P - P | Alan Grahame Memorial | Perry Barr Stadium |
| 2022-09-14 19:30:44Wednesday, September 14, 2022 | Birmingham Brummies v Cradley Heathens Select | 19:30:447:30 pm | 55 - 35 | Alan Grahame Memorial | Perry Barr Stadium |
