| 2022-03-30 19:30:58Wednesday, March 30, 2022 | Poole Pirates v Peterborough Panthers | 19:30:587:30 pm | 55 - 35 | Bjarne Pedersen Farewell | Poole Stadium |
| 2022-04-05 19:00:00Tuesday, April 5, 2022 | Plymouth Gladiators v Poole Pirates | 19:00:007:00 pm | 42 - 48 | Championship KO Cup, Quarter-Final, 1st Leg | Plymouth Coliseum |
| 2022-04-06 19:30:00Wednesday, April 6, 2022 | Poole Pirates v Plymouth Gladiators | 19:30:007:30 pm | 58 - 32 | Championship KO Cup, Quarter-Final, 2nd Leg | Poole Stadium |
| 2022-04-13 14:50:00Wednesday, April 13, 2022 | Birmingham Brummies v Poole Pirates | 14:50:00Postponed | P - P | Championship | Perry Barr Stadium |
| 2022-04-15 19:30:00Friday, April 15, 2022 | Poole Pirates v Oxford Cheetahs | 19:30:007:30 pm | 58 - 32 | Championship | Poole Stadium |
| 2022-04-16 19:00:00Saturday, April 16, 2022 | Leicester Lions v Poole Pirates | 19:00:007:00 pm | 48 - 42 | Championship | Paul Chapman & Sons Arena |
| 2022-04-20 19:30:00Wednesday, April 20, 2022 | Oxford Cheetahs v Poole Pirates | 19:30:007:30 pm | 42 - 48 | Championship | Oxford Stadium |
| 2022-04-27 19:30:00Wednesday, April 27, 2022 | Poole Pirates v Birmingham Brummies | 19:30:007:30 pm | 54 - 36 | Championship | Poole Stadium |
| 2022-05-03 19:00:00Tuesday, May 3, 2022 | Plymouth Gladiators v Poole Pirates | 19:00:007:00 pm | 53 - 37 | Championship | Plymouth Coliseum |
| 2022-05-11 19:30:00Wednesday, May 11, 2022 | Poole Pirates v Newcastle Diamonds | 19:30:007:30 pm | 58 - 32 | Championship | Poole Stadium |
| 2022-05-13 19:30:00Friday, May 13, 2022 | Redcar Bears v Poole Pirates | 19:30:007:30 pm | 40 - 50 | Championship | ECCO Arena |
| 2022-05-18 11:38:00Wednesday, May 18, 2022 | Poole Pirates v Berwick Bandits | 11:38:00Postponed | P - P | Championship | Poole Stadium |
| 2022-05-20 19:30:00Friday, May 20, 2022 | Glasgow Tigers v Poole Pirates | 19:30:007:30 pm | 45 - 45 | Championship | Peugeot Ashfield Stadium |
| 2022-05-25 19:30:05Wednesday, May 25, 2022 | Birmingham Brummies v Poole Pirates | 19:30:057:30 pm | 35 - 55 | Championship | Perry Barr Stadium |
| 2022-06-01 19:30:00Wednesday, June 1, 2022 | Poole Pirates v Edinburgh Monarchs | 19:30:007:30 pm | 49 - 41 | Championship | Poole Stadium |
| 2022-06-08 19:30:00Wednesday, June 8, 2022 | Poole Pirates v Leicester Lions | 19:30:007:30 pm | 43 - 47 | Championship | Poole Stadium |
| 2022-06-17 19:30:00Friday, June 17, 2022 | Scunthorpe Scorpions v Poole Pirates | 19:30:007:30 pm | 45 - 44 | Championship | Eddie Wright Raceway |
| 2022-06-22 19:30:00Wednesday, June 22, 2022 | Poole Pirates v Plymouth Gladiators | 19:30:007:30 pm | 45 - 45 | Championship | Poole Stadium |
| 2022-06-29 19:30:14Wednesday, June 29, 2022 | Poole Pirates v Berwick Bandits | 19:30:147:30 pm | 49 - 41 | Championship | Poole Stadium |
| 2022-07-08 19:30:00Friday, July 8, 2022 | Edinburgh Monarchs v Poole Pirates | 19:30:007:30 pm | 49 - 41 | Championship | Armadale Stadium |
| 2022-07-09 19:30:00Saturday, July 9, 2022 | Berwick Bandits v Poole Pirates | 19:30:007:30 pm | 45 - 45 | Championship | Shielfield Park |
| 2022-07-13 19:30:00Wednesday, July 13, 2022 | Poole Pirates v Glasgow Tigers | 19:30:007:30 pm | 51 - 39 | Championship | Poole Stadium |
| 2022-07-19 19:00:00Tuesday, July 19, 2022 | Plymouth Gladiators v Poole Pirates | 19:00:007:00 pm | 39 - 51 | Championship Jubilee League (Southern) | Plymouth Coliseum |
| 2022-07-20 19:30:00Wednesday, July 20, 2022 | Poole Pirates v Scunthorpe Scorpions | 19:30:007:30 pm | 55 - 35 | Championship | Poole Stadium |
| 2022-07-27 19:30:00Wednesday, July 27, 2022 | Birmingham Brummies v Poole Pirates | 19:30:007:30 pm | 34 - 56 | Championship Jubilee League (Southern) | Perry Barr Stadium |
| 2022-07-29 19:30:00Friday, July 29, 2022 | Poole Pirates v Birmingham Brummies | 19:30:007:30 pm | 59 - 31 | Championship Jubilee League (Southern) | Poole Stadium |
| 2022-08-02 19:30:00Tuesday, August 2, 2022 | Oxford Cheetahs v Poole Pirates | 19:30:007:30 pm | 45 - 45 | Championship Jubilee League (Southern) | Oxford Stadium |
| 2022-08-03 19:30:00Wednesday, August 3, 2022 | Poole Pirates v Oxford Cheetahs | 19:30:007:30 pm | 48 - 42 | Championship Jubilee League (Southern) | Poole Stadium |
| 2022-08-10 19:30:00Wednesday, August 10, 2022 | Poole Pirates v Plymouth Gladiators | 19:30:007:30 pm | 62 - 28 | Championship Jubilee League (Southern) | Poole Stadium |
| 2022-08-17 19:30:00Wednesday, August 17, 2022 | Poole Pirates v Redcar Bears | 19:30:007:30 pm | 55 - 34 | Championship | Poole Stadium |
| 2022-08-31 19:30:44Wednesday, August 31, 2022 | Neil Middleditch Testimonial @ Poole | 19:30:447:30 pm | 39 - 51 | Neil Middleditch Testimonial | Poole Stadium |
| 2022-09-06 00:05:29Tuesday, September 6, 2022 | Plymouth Gladiators v Poole Pirates | 00:05:29Postponed | P - P | Championship Play-Off, Quarter-Final, 1st Leg | Plymouth Coliseum |
| 2022-09-07 18:30:49Wednesday, September 7, 2022 | Poole Pirates v Plymouth Gladiators | 18:30:49Postponed | P - P | Championship Play-Off, Quarter-Final, 1st Leg | Poole Stadium |
| 2022-09-10 00:05:13Saturday, September 10, 2022 | Leicester Lions v Poole Pirates | 00:05:13Postponed | P - P | Championship KO Cup, Semi-Final, 1st Leg | Paul Chapman & Sons Arena |
| 2022-09-13 09:00:43Tuesday, September 13, 2022 | Plymouth Gladiators v Poole Pirates | 09:00:43Postponed | P - P | Championship Play-Off, Quarter-Final, 1st Leg | Plymouth Coliseum |
| 2022-09-14 19:30:04Wednesday, September 14, 2022 | Poole Pirates v Plymouth Gladiators | 19:30:047:30 pm | 60 - 30 | Championship Play-Off, Quarter-Final, 1st Leg | Poole Stadium |
| 2022-09-17 19:00:25Saturday, September 17, 2022 | Leicester Lions v Poole Pirates | 19:00:257:00 pm | 46 - 44 | Championship KO Cup, Semi-Final, 1st Leg | Paul Chapman & Sons Arena |
| 2022-09-20 19:00:41Tuesday, September 20, 2022 | Plymouth Gladiators v Poole Pirates | 19:00:417:00 pm | 40 - 50 | Championship Play-Off, Quarter-Final, 2nd Leg | Plymouth Coliseum |
| 2022-09-21 19:30:54Wednesday, September 21, 2022 | Poole Pirates v Leicester Lions | 19:30:547:30 pm | 60 - 30 | Championship KO Cup, Semi-Final, 2nd Leg | Poole Stadium |
| 2022-09-25 18:00:42Sunday, September 25, 2022 | Glasgow Tigers v Poole Pirates | 18:00:42Abandoned | 17 - 13 | Championship Play-Off, Semi-Final, 1st Leg | Peugeot Ashfield Stadium |
| 2022-09-28 19:30:45Wednesday, September 28, 2022 | Poole Pirates v Glasgow Tigers | 19:30:457:30 pm | 60 - 30 | Championship Play-Off, Semi-Final, 1st Leg | Poole Stadium |
| 2022-10-01 00:02:56Saturday, October 1, 2022 | Glasgow Tigers v Poole Pirates | 00:02:56Postponed | P - P | Championship Play-Off, Semi-Final, 2nd Leg | Peugeot Ashfield Stadium |
| 2022-10-02 18:00:55Sunday, October 2, 2022 | Glasgow Tigers v Poole Pirates | 18:00:556:00 pm | 39 - 50 | Championship Play-Off, Semi-Final, 2nd Leg | Peugeot Ashfield Stadium |
| 2022-10-07 19:30:42Friday, October 7, 2022 | Redcar Bears v Poole Pirates | 19:30:427:30 pm | 41 - 48 | Championship KO Cup Final, 1st Leg | ECCO Arena |
| 2022-10-12 19:30:11Wednesday, October 12, 2022 | Poole Pirates v Redcar Bears | 19:30:117:30 pm | 52 - 38 | Championship KO Cup Final, 2nd Leg | Poole Stadium |
| 2022-10-21 00:05:50Friday, October 21, 2022 | Poole Pirates v Leicester Lions | 00:05:50Postponed | P - P | Championship Grand Final, 1st Leg | Poole Stadium |
| 2022-10-22 11:00:27Saturday, October 22, 2022 | Leicester Lions v Poole Pirates | 11:00:27Postponed | P - P | Championship Grand Final, 1st Leg | Paul Chapman & Sons Arena |
| 2022-10-26 19:30:21Wednesday, October 26, 2022 | Poole Pirates v Leicester Lions | 19:30:217:30 pm | 49 - 41 | Championship Grand Final, 1st Leg | Poole Stadium |
| 2022-10-29 09:15:29Saturday, October 29, 2022 | Leicester Lions v Poole Pirates | 09:15:29Postponed | P - P | Championship Grand Final, 2nd Leg | Paul Chapman & Sons Arena |
| 2022-10-30 09:43:31Sunday, October 30, 2022 | Leicester Lions v Poole Pirates | 09:43:31Postponed | P - P | Championship Grand Final, 2nd Leg | Paul Chapman & Sons Arena |
| 2022-11-04 19:00:39Friday, November 4, 2022 | Leicester Lions v Poole Pirates | 19:00:397:00 pm | 38 - 52 | Championship Grand Final, 2nd Leg | Adrian Flux Arena |
