| 2021-05-17 19:30:45Monday, May 17, 2021 | Belle Vue Aces v Sheffield Tigers | 19:30:457:30 pm | 47 - 43 | Premiership | National Speedway Stadium |
| 2021-05-20 09:30:05Thursday, May 20, 2021 | Sheffield Tigers v Peterborough Panthers | 09:30:05Postponed | P - P | Premiership | Owlerton Stadium |
| 2021-05-24 11:40:46Monday, May 24, 2021 | Peterborough Panthers v Sheffield Tigers | 11:40:46Postponed | P - P | Premiership | East of England Arena |
| 2021-05-27 19:30:26Thursday, May 27, 2021 | Ipswich Witches v Sheffield Tigers | 19:30:267:30 pm | 51 - 39 | Premiership | Foxhall Heath Stadium |
| 2021-06-03 19:30:35Thursday, June 3, 2021 | Sheffield Tigers v Wolverhampton Wolves | 19:30:357:30 pm | 49 - 41 | Premiership | Owlerton Stadium |
| 2021-06-07 19:30:56Monday, June 7, 2021 | Wolverhampton Wolves v Sheffield Tigers | 19:30:567:30 pm | 50 - 40 | Premiership | Monmore Green |
| 2021-06-17 00:05:58Thursday, June 17, 2021 | King's Lynn Stars v Sheffield Tigers | 00:05:58Postponed | P - P | Premiership | Adrian Flux Arena |
| 2021-06-24 19:30:05Thursday, June 24, 2021 | Sheffield Tigers v Ipswich Witches | 19:30:057:30 pm | 48 - 42 | Premiership | Owlerton Stadium |
| 2021-06-28 19:30:46Monday, June 28, 2021 | Peterborough Panthers v Sheffield Tigers | 19:30:467:30 pm | 54 - 36 | Premiership | East of England Arena |
| 2021-07-01 19:30:35Thursday, July 1, 2021 | Sheffield Tigers v Belle Vue Aces | 19:30:357:30 pm | 46 - 44 | Premiership | Owlerton Stadium |
| 2021-07-05 19:30:56Monday, July 5, 2021 | Wolverhampton Wolves v Sheffield Tigers | 19:30:567:30 pm | 48 - 42 | Premiership | Monmore Green |
| 2021-07-12 00:05:46Monday, July 12, 2021 | Peterborough Panthers v Sheffield Tigers | 00:05:46Postponed | P - P | Premiership | East of England Arena |
| 2021-07-15 19:30:05Thursday, July 15, 2021 | Sheffield Tigers v King's Lynn Stars | 19:30:057:30 pm | 46 - 44 | Premiership | Owlerton Stadium |
| 2021-07-22 19:30:05Thursday, July 22, 2021 | Sheffield Tigers v Peterborough Panthers | 19:30:057:30 pm | 40 - 50 | Premiership | Owlerton Stadium |
| 2021-08-02 19:30:58Monday, August 2, 2021 | King's Lynn Stars v Sheffield Tigers | 19:30:587:30 pm | 41 - 49 | Premiership | Adrian Flux Arena |
| 2021-08-09 19:30:26Monday, August 9, 2021 | Ipswich Witches v Sheffield Tigers | 19:30:267:30 pm | 41 - 49 | Premiership | Foxhall Heath Stadium |
| 2021-08-12 19:30:35Thursday, August 12, 2021 | Sheffield Tigers v Wolverhampton Wolves | 19:30:357:30 pm | 44 - 46 | Premiership | Owlerton Stadium |
| 2021-08-19 19:30:46Thursday, August 19, 2021 | King’s Lynn Stars v Sheffield Tigers | 19:30:46Postponed | P - P | Premiership | Adrian Flux Arena |
| 2021-08-26 19:30:05Thursday, August 26, 2021 | Sheffield Tigers v Ipswich Witches | 19:30:057:30 pm | 52 - 38 | Premiership | Owlerton Stadium |
| 2021-09-02 19:30:35Thursday, September 2, 2021 | Sheffield Tigers v Belle Vue Aces | 19:30:357:30 pm | 49 - 41 | Premiership | Owlerton Stadium |
| 2021-09-06 19:30:09Monday, September 6, 2021 | Belle Vue Aces v Sheffield Tigers | 19:30:097:30 pm | 54 - 36 | Premiership | National Speedway Stadium |
| 2021-09-09 19:30:44Thursday, September 9, 2021 | King’s Lynn Stars v Sheffield Tigers | 19:30:447:30 pm | 45 - 45 | Premiership | Adrian Flux Arena |
| 2021-09-16 19:30:52Thursday, September 16, 2021 | Sheffield Tigers v Peterborough Panthers | 19:30:527:30 pm | 40 - 50 | Premiership | Owlerton Stadium |
| 2021-09-20 19:30:25Monday, September 20, 2021 | Peterborough Panthers v Sheffield Tigers | 19:30:257:30 pm | 39 - 51 | Premiership | East of England Arena |
| 2021-09-26 17:00:06Sunday, September 26, 2021 | Sheffield Tigers v King’s Lynn Stars | 17:00:065:00 pm | 61 - 29 | Premiership | Owlerton Stadium |
| 2021-09-30 17:19:02Thursday, September 30, 2021 | Sheffield Tigers v Belle Vue Aces | 17:19:02Postponed | P - P | Premiership Play-Off, Semi-Final, 1st Leg | Owlerton Stadium |
| 2021-10-04 19:30:46Monday, October 4, 2021 | Sheffield Tigers v Belle Vue Aces | 19:30:467:30 pm | 40 - 50 | Premiership Play-Off, Semi-Final, 1st Leg | Owlerton Stadium |
| 2021-10-07 19:30:34Thursday, October 7, 2021 | Belle Vue Aces v Sheffield Tigers | 19:30:347:30 pm | 48 - 42 | Premiership Play-Off, Semi-Final, 2nd Leg | National Speedway Stadium |
