| 2022-03-30 19:30:58Wednesday, March 30, 2022 | Poole Pirates v Peterborough Panthers | 19:30:587:30 pm | 55 - 35 | Bjarne Pedersen Farewell | Poole Stadium |
| 2022-04-05 19:00:00Tuesday, April 5, 2022 | Plymouth Gladiators v Poole Pirates | 19:00:007:00 pm | 42 - 48 | Championship KO Cup, Quarter-Final, 1st Leg | Plymouth Coliseum |
| 2022-04-06 19:30:00Wednesday, April 6, 2022 | Poole Pirates v Plymouth Gladiators | 19:30:007:30 pm | 58 - 32 | Championship KO Cup, Quarter-Final , 2nd Leg | Poole Stadium |
| 2022-04-13 14:50:00Wednesday, April 13, 2022 | Birmingham Brummies v Poole Pirates | 14:50:00Postponed | P - P | Championship | Perry Barr Stadium |
| 2022-04-15 19:30:00Friday, April 15, 2022 | Poole Pirates v Oxford Cheetahs | 19:30:007:30 pm | 58 - 32 | Championship | Poole Stadium |
| 2022-04-16 19:00:00Saturday, April 16, 2022 | Leicester Lions v Poole Pirates | 19:00:007:00 pm | 48 - 42 | Championship | Paul Chapman & Sons Arena |
| 2022-04-20 19:30:00Wednesday, April 20, 2022 | Oxford Cheetahs v Poole Pirates | 19:30:007:30 pm | 42 - 48 | Championship | Oxford Stadium |
| 2022-04-27 19:30:00Wednesday, April 27, 2022 | Poole Pirates v Birmingham Brummies | 19:30:007:30 pm | 54 - 36 | Championship | Poole Stadium |
| 2022-05-03 19:00:00Tuesday, May 3, 2022 | Plymouth Gladiators v Poole Pirates | 19:00:007:00 pm | 53 - 37 | Championship | Plymouth Coliseum |
| 2022-05-11 19:30:00Wednesday, May 11, 2022 | Poole Pirates v Newcastle Diamonds | 19:30:007:30 pm | 58 - 32 | Championship | Poole Stadium |
| 2022-05-13 19:30:00Friday, May 13, 2022 | Redcar Bears v Poole Pirates | 19:30:007:30 pm | 40 - 50 | Championship | ECCO Arena |
| 2022-05-18 11:38:00Wednesday, May 18, 2022 | Poole Pirates v Berwick Bandits | 11:38:00Postponed | P - P | Championship | Poole Stadium |
| 2022-05-20 19:30:00Friday, May 20, 2022 | Glasgow Tigers v Poole Pirates | 19:30:007:30 pm | 45 - 45 | Championship | Peugeot Ashfield Stadium |
| 2022-05-25 19:30:05Wednesday, May 25, 2022 | Birmingham Brummies v Poole Pirates | 19:30:057:30 pm | 35 - 55 | Championship | Perry Barr Stadium |
| 2022-06-01 19:30:00Wednesday, June 1, 2022 | Poole Pirates v Edinburgh Monarchs | 19:30:007:30 pm | 49 - 41 | Championship | Poole Stadium |
| 2022-06-08 19:30:00Wednesday, June 8, 2022 | Poole Pirates v Leicester Lions | 19:30:007:30 pm | 43 - 47 | Championship | Poole Stadium |
| 2022-06-17 19:30:00Friday, June 17, 2022 | Scunthorpe Scorpions v Poole Pirates | 19:30:007:30 pm | 45 - 44 | Championship | Eddie Wright Raceway |
| 2022-06-22 19:30:00Wednesday, June 22, 2022 | Poole Pirates v Plymouth Gladiators | 19:30:007:30 pm | 45 - 45 | Championship | Poole Stadium |
| 2022-06-29 19:30:14Wednesday, June 29, 2022 | Poole Pirates v Berwick Bandits | 19:30:147:30 pm | 49 - 41 | Championship | Poole Stadium |
| 2022-07-08 19:30:00Friday, July 8, 2022 | Edinburgh Monarchs v Poole Pirates | 19:30:007:30 pm | - | Championship | Armadale Stadium |
| 2022-07-09 19:30:00Saturday, July 9, 2022 | Berwick Bandits v Poole Pirates | 19:30:007:30 pm | - | Championship | Shielfield Park |
| 2022-07-13 19:30:00Wednesday, July 13, 2022 | Poole Pirates v Glasgow Tigers | 19:30:007:30 pm | - | Championship | Poole Stadium |
| 2022-07-19 19:00:00Tuesday, July 19, 2022 | Plymouth Gladiators v Poole Pirates | 19:00:007:00 pm | - | Summer Trophy (Southern) | Plymouth Coliseum |
| 2022-07-20 19:30:00Wednesday, July 20, 2022 | Poole Pirates v Scunthorpe Scorpions | 19:30:007:30 pm | - | Championship | Poole Stadium |
| 2022-07-27 19:30:00Wednesday, July 27, 2022 | Birmingham Brummies v Poole Pirates | 19:30:007:30 pm | - | Summer Trophy (Southern) | Perry Barr Stadium |
| 2022-07-29 19:30:00Friday, July 29, 2022 | Poole Pirates v Birmingham Brummies | 19:30:007:30 pm | - | Summer Trophy (Southern) | Poole Stadium |
| 2022-08-02 19:30:00Tuesday, August 2, 2022 | Oxford Cheetahs v Poole Pirates | 19:30:007:30 pm | - | Summer Trophy (Southern) | Oxford Stadium |
| 2022-08-03 19:30:00Wednesday, August 3, 2022 | Poole Pirates v Oxford Cheetahs | 19:30:007:30 pm | - | Summer Trophy (Southern) | Poole Stadium |
| 2022-08-10 19:30:00Wednesday, August 10, 2022 | Poole Pirates v Plymouth Gladiators | 19:30:007:30 pm | - | Summer Trophy (Southern) | Poole Stadium |
| 2022-08-17 19:30:00Wednesday, August 17, 2022 | Poole Pirates v Redcar Bears | 19:30:007:30 pm | - | Championship | Poole Stadium |
| 2022-08-31 19:30:44Wednesday, August 31, 2022 | Neil Middleditch Testimonial @ Poole | 19:30:447:30 pm | - | Neil Middleditch Testimonial | Poole Stadium |
