| 2022-04-09 19:00:00Saturday, April 9, 2022 | Berwick Bullets v Oxford Chargers | 19:00:007:00 pm | 50 - 40 | National Development League | Shielfield Park |
| 2022-05-04 19:30:00Wednesday, May 4, 2022 | Oxford Chargers v Berwick Bullets | 19:30:007:30 pm | 50 - 39 | National Development League | Oxford Stadium |
| 2022-05-06 19:30:00Friday, May 6, 2022 | Armadale Devils v Oxford Chargers | 19:30:007:30 pm | 42 - 48 | National Development League | Armadale Stadium |
| 2022-06-01 19:30:00Wednesday, June 1, 2022 | Oxford Chargers v Plymouth Centurions | 19:30:007:30 pm | 50 - 39 | National Development League | Oxford Stadium |
| 2022-06-03 13:00:00Friday, June 3, 2022 | Belle Vue Colts v Oxford Chargers | 13:00:001:00 pm | 57 - 33 | National Development League | National Speedway Stadium |
| 2022-06-14 19:00:00Tuesday, June 14, 2022 | Plymouth Centurions v Oxford Chargers | 19:00:007:00 pm | 34 - 56 | National Development League | Plymouth Coliseum |
| 2022-07-09 19:00:00Saturday, July 9, 2022 | Leicester Lion Cubs v Oxford Chargers | 19:00:007:00 pm | 51 - 39 | National Development League | Paul Chapman & Sons Arena |
| 2022-07-20 19:30:00Wednesday, July 20, 2022 | Oxford Chargers v Leicester Lion Cubs | 19:30:007:30 pm | 45 - 45 | National Development League | Oxford Stadium |
| 2022-07-24 12:00:00Sunday, July 24, 2022 | Kent Royals v Oxford Chargers | 12:00:0012:00 pm | 42 - 47 | National Development League | Iwade Stadium |
| 2022-08-03 19:30:00Wednesday, August 3, 2022 | Oxford Chargers v Armadale Devils | 19:30:007:30 pm | 65 - 25 | National Development League | Oxford Stadium |
| 2022-08-10 19:30:00Wednesday, August 10, 2022 | Oxford Chargers v Belle Vue Colts | 19:30:007:30 pm | 48 - 41 | National Development League | Oxford Stadium |
| 2022-08-24 19:30:00Wednesday, August 24, 2022 | Oxford Chargers v Mildenhall Fen Tigers | 19:30:007:30 pm | 39 - 51 | National Development League | Oxford Stadium |
| 2022-08-28 15:00:00Sunday, August 28, 2022 | Mildenhall Fen Tigers v Oxford Chargers | 15:00:003:00 pm | 55 - 32 | National Development League | Mildenhall Stadium |
| 2022-09-07 16:30:00Wednesday, September 7, 2022 | Oxford Chargers v Kent Royals | 16:30:00Postponed | P - P | National Development League | Oxford Stadium |
| 2022-09-21 19:30:27Wednesday, September 21, 2022 | Oxford Chargers v Kent Royals | 19:30:277:30 pm | 60 - 29 | National Development League | Oxford Stadium |
| 2022-10-05 19:30:10Wednesday, October 5, 2022 | Oxford Chargers v Leicester Lion Cubs | 19:30:107:30 pm | 46 - 44 | NDL Play-Off, Semi-Final, 1st leg | Oxford Stadium |
| 2022-10-08 19:00:35Saturday, October 8, 2022 | Leicester Lion Cubs v Oxford Chargers | 19:00:357:00 pm | 52 - 38 | NDL Play-Off, Semi-Final, 2nd leg | Paul Chapman & Sons Arena |
